Building the intelligence layer for chronic pain care

DavantAI is developing a multimodal digital twin of pain and two connected AI-Assistants to help make chronic pain more measurable, understandable and actionable over time.

Starting with chronic pain. Building toward the Pain Intelligence Platform.

Academic, clinical and patient-grounded collaboration

One of healthcare's largest unresolved challenges

Chronic pain affects millions of people and remains one of the most difficult conditions to understand and manage over time.

For patients, the burden is continuous. For clinicians, the picture is often fragmented. Pain changes between visits, across contexts and under the influence of many interacting factors — yet the system still lacks a clear, longitudinal understanding of that evolution.

Pain is dynamic, not static

Clinical visibility is episodic

Context is often missing

Personalization remains limited

Chronic pain is one of the world's largest health burdens

619 M

People with low back pain worldwide (WHO, 2020)

24.3 %

US adults living with chronic pain (CDC, 2023)

150 M

People with chronic pain in Europe (EFIC)

What chronic pain care lacks is not just more attention. It lacks intelligence.

Today, chronic pain is still captured through fragmented signals: isolated consultations, partial self-reporting, limited continuity and little contextual understanding of what happens between clinical encounters.

Without a patient-specific and longitudinal intelligence layer, it remains difficult to understand how pain evolves, what influences it and how treatment decisions are performing over time.

DavantAI is building that missing layer.

A multimodal digital twin of pain

At the core of DavantAI is a patient-specific digital twin designed to learn the dynamics of pain over time. It integrates multiple streams of information — wearable signals, smartphone-based context and patient-derived information — into a richer, more continuous understanding of each patient’s pain journey.

The goal is not merely to collect data, but to transform fragmented signals into longitudinal pain intelligence.

Multimodal inputs

Wearable signals, smartphone-based context and patient-derived interaction over time.

Pain digital twin

A patient-specific model that learns the dynamics of each person’s pain over time.

Longitudinal intelligence

Continuous insight, contextual understanding and a new layer for personalization.

Two connected AI-Assistants. One intelligence layer.

The first applications of our pain digital twin are two connected AI-Assistants: one for patients, and one for clinicians. Together, they create a continuous loop of support, insight and learning.

Not two separate tools, but two interfaces connected by the same evolving intelligence system: patients gain continuity, clinicians gain context, and the model keeps learning.

From digital twin to Pain Intelligence Platform

Digital twin + AI-Assistants

We start with a multimodal pain digital twin and two connected AI-Assistants — one for patients, one for clinicians.

A growing intelligence layer

As more patient journeys, interactions and multimodal signals feed the system, the underlying intelligence keeps improving.

Pain Intelligence Platform

The layer scales into a platform and, long term, helps lay the groundwork for the foundational model of pain.

Built with clinical, scientific and patient-grounded collaboration

DavantAI is being shaped through collaboration with academic researchers, clinical institutions and patient communities — because building meaningful pain intelligence requires more than technology alone. This is not innovation in isolation: it is being built in the right environment, with the right stakeholders.

Academic foundations

Grounded in scientific and technical expertise, with founding ties to leading Spanish universities, including UPM and UCM.

Clinical collaboration

Developed in dialogue with top-tier clinical institutions working directly with chronic pain care pathways.

Patient communities

Informed by collaboration with patient associations to stay close to the lived reality of chronic pain.

Ecosystem support

Connected to the broader health-innovation ecosystem, including Barcelona Health Hub, through strategic relationships and expert supporters.

From thesis to real-world validation

Concept, MVP and early validation

Concept development, an early MVP, and structured feedback from clinicians and patients.

First digital twin and AI-Assistants

First version of the digital twin and the first connected AI-Assistants in selected chronic pain indications.

Toward the Pain Intelligence Platform

Platform expansion, broader learning loops and long-term Pain Intelligence development.

We are looking to collaborate with forward-thinking partners

We believe chronic pain needs a new generation of intelligence infrastructure — and that meaningful progress will come through collaboration across clinical care, health systems, insurers, digital health and research. If you are exploring how chronic pain can be understood, supported and treated in more intelligent ways, we would welcome the conversation.

Frequently asked questions

DavantAI is building a new intelligence layer for chronic pain care. At its core is a multimodal digital twin of pain, and its first applications are two connected AI-Assistants — one for patients, one for clinicians. Long term, we are building toward a Pain Intelligence Platform.